HbA1C

What is dangerous HbA1C level ? How to manage that?

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An HbA1C blood test or A1C test measures the average blood sugar level for the past 3 months or 90 days. The American Diabetes Association (ADA) recommends using A1C tests to diagnose prediabetes, type 1 diabetes, and type 2 diabetes.

Hb (Hemoglobin) is a protein found in RBC (red blood cells), whose role is transporting oxygen to cells. HbA1C is the portion of hemoglobin that takes up sugar in the blood. The high level may be a sign of poorly controlled diabetes.

High A1C levels are a risk for diabetes and other complications. However, ideal and dangerous A1C levels can vary slightly between each individual. Lifestyle changes can help manage A1C levels.

The HbA1C test, also known as the haemoglobin A1C, HbA1C, glycated haemoglobin, or glycohaemoglobin test, measures the amount of sugar attached to haemoglobin in the blood.Haemoglobin is a protein present in red blood cells (RBCs), and sugar naturally attaches to it. However, as people with higher blood sugar levels have more sugar-coated haemoglobin, it is a useful test to help check and monitor diabetes status.

As higher A1C levels are often associated with diabetes complications, it is important to reach and maintain target A1C results. An individual’s personal A1C goal will depend on many factors, including age and any other medical conditions. Although it is an important tool for managing diabetes, testing A1C levels does not replace other strategies, such as regular blood sugar testing at home.

The doctor relies on A1C tests to monitor diabetes treatment plans. If your aAc11C levels are too high, this means your blood sugar is too high. Lowering blood sugar levels lowers a person’s A1C. To understand how to lower HbA1c level, it’s important to understand what is glycated hemoglobin or A1C.

A person can work toward lowering and maintaining their A1C level by following their treatment plan, getting regular physical exercise, and taking steps to lose weight, if the doctor has advised doing so.

HbA1C test works

What is HbA1C, and what does it measure?

The HbA1C test is a blood test that measures a person’s average blood sugar levels over the past 3 months. In particular, it measures the percentage of haemoglobin in the blood with an attached molecule of glucose.

When glucose attaches to haemoglobin, experts refer to the resulting compound as glycosylated haemoglobin. The name of the test derives from the fact that about 95–98% of the haemoglobin present in the body is type A1. Type A1 haemoglobin has subtypes, including A1C. As this is the most abundant subtype, it is a good marker for glucose control.

The test uses a 3-month average because RBCs typically live for about 3 months. Therefore, this timeframe reflects the sugar exposure to the cells over that time. The test does not require any specific preparations, so a person does not need to fast prior to the test, and a doctor can perform it at any time of the day.

HbA1C test works

How the HbA1C test works

The HbA1C test estimates the average blood sugar level over the past 3 months. The test is able to measure this by identifying the percentage of glycosylated haemoglobin in the blood.

If there is more glucose present in the blood, more glucose is available to attach to haemoglobin. Therefore, if a person has a high percentage of glycosylated haemoglobin, it indicates that they have had high blood sugar for an extended period.

What are dangerous HbA1c levels?

HbA1C test results represent how well the body is maintaining blood glucose levels by showing the average percentage of sugar-bound haemoglobin in a blood sample. A higher A1C level suggests a higher risk of diabetes and its complications.

When discussing A1C levels, a doctor may also refer to estimated average glucose, or eAG. The eAG corresponds to A1C, but it appears as milligrams per deciliter (mg/dl), as with blood sugar. Both HbA1C and eAG refer to a person’s average 3-month blood glucose levels.

HbA1C value eAG value Potential diagnosis
5.6% or less 117 mg/dl or less Normal
5.7–6.4% 117–137 mg/dl Prediabetes
6.5% or more 137 mg/dl Diabetes

However, A1C level recommendations can vary among individuals due to a number of factors. What may be high for one person might be within range for another person.

For example, people with more advanced diabetes will have higher A1C targets than those without diabetes. Various underlying conditions, including blood disorders, can also have an effect, as can potentially modifiable factors, such as stress, medications, and lifestyle changes.

A1C value eAG value Potential targets :
5.6% or below 117 mg/dl or below healthy adults without diabetes
6.5% 140 mg/dl people with short-term diabetes, managed type 2 diabetes, no cardiovascular disease, long life expectancy
7% or less 154 mg/dl or less most non-pregnant adults with diabetes
8% or less 183 mg/dl or less people with long-standing or severe diabetes, limited life expectancy, extensive additional health complications, or poor treatment response

A person with an A1C level indicating prediabetes may wish to consider making lifestyle changes, such as adopting a well-balanced diet and staying active, to help manage or even reverse the condition before it progresses to type 2 diabetes.

If a person has a higher HbA1C level, suggesting diabetes, it is advisable for them to contact a doctor. The doctor will be able to run further diagnostic tests to confirm the person’s diabetes status.

The A1C goal for most people with diabetes is 7% or less. However, personal targets can vary, and a diabetes care team may consider other factors to help a person set their own individual goals.

If a person with diabetes has an A1C test result that is much higher than their set target, a doctor can help advise lifestyle and medication changes to lower their A1C level.

Complications of high HbA1C

A high A1C level can be concerning, as it may indicate that an individual has a higher risk of diabetes complications. For those without a diabetes diagnosis, it suggests that, without interventions, they may develop the condition. For individuals living with diabetes, it may indicate that their current treatment plan is not effective and that they should contact a doctor.

Potential complications that can result from high blood sugar levels :

  • kidney disease
  • eye disease
  • stroke and cardiovascular disease
  • metabolic syndrome
  • neuropathy

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